7JGJ

IgA1 Protease in complex with neutralizing mAb

Summary for 7JGJ

• Entry DOI: 10.2210/pdb7jgj/pdb
• EMDB information: 22328
• Descriptor: Immunoglobulin A1 protease, mAB Light Chain, mAB Heavy Chain (3 entities in total)
• Functional Keywords: iga1, protease, neutralization, immune system
• Biological source: Streptococcus pneumoniae; More
• Total number of polymer chains: 3
• Total formula weight: 191578.43

Authors

Eisenmesser, E.Z.,Zheng, H. (deposition date: 2020-07-19, release date: 2020-12-09)

• Primary citation: Wang, Z.,Rahkola, J.,Redzic, J.S.,Chi, Y.C.,Tran, N.,Holyoak, T.,Zheng, H.,Janoff, E.,Eisenmesser, E.Z.; Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease; Nat Commun, 11:6063-, 2020; PubMed: 33247098; DOI: 0.1038/s41467-020-19887-3

Experimental method

ELECTRON MICROSCOPY (4.8 Å)