7EMG

Carbonyl Reductase Variant 4 (R123C/L209P/F183Y/V61K) from Serratia marcescens complexed with NADP+

Summary for 7EMG

Entry DOI	10.2210/pdb7emg/pdb
Descriptor	3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	nadp+ complex, carbonyl reductase, oxidoreductase
Biological source	Serratia marcescens
Total number of polymer chains	2
Total formula weight	54801.77
Authors	Zheng, Y.C.,Wang, T.,Bai, Y.P. (deposition date: 2021-04-14, release date: 2021-10-06, Last modification date: 2023-11-29)
Primary citation	Wang, T.,Zhang, X.Y.,Zheng, Y.C.,Bai, Y.P. Stereoselective synthesis of chiral delta-lactones via an engineered carbonyl reductase. Chem.Commun.(Camb.), 57:10584-10587, 2021 Cited by PubMed: 34559867 DOI: 10.1039/d1cc04542c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.449 Å)

Structure validation