7EMG
Carbonyl Reductase Variant 4 (R123C/L209P/F183Y/V61K) from Serratia marcescens complexed with NADP+
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 3-oxoacyl-[acyl-carrier-protein] reductase | polymer | 252 | 26624.4 | 2 | UniProt (A0A0G8B235) Pfam (PF13561) In PDB | Serratia marcescens | |
2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 244 (UniProt: A0A0G8B235)
PDB | External Database | Details |
---|---|---|
Met -7 | - | initiating methionine |
Gly -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Lys 61 | Val 61 | engineered mutation |
Cys 123 | Arg 123 | engineered mutation |
Tyr 183 | Phe 183 | engineered mutation |
Pro 209 | Leu 209 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 53248.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1552.9 | |
All* | Total formula weight | 54801.8 |