7C2N

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SPIRO

Summary for 7C2N

Entry DOI	10.2210/pdb7c2n/pdb
Descriptor	Drug exporters of the RND superfamily-like protein,Endolysin, alpha-D-glucopyranosyl 6-O-dodecyl-alpha-D-glucopyranoside, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, ... (4 entities in total)
Functional Keywords	membrane protein
Biological source	Mycolicibacterium smegmatis MC2 155 More
Total number of polymer chains	1
Total formula weight	106297.35
Authors	Zhang, B.,Yang, X.,Hu, T.,Rao, Z. (deposition date: 2020-05-08, release date: 2020-12-02, Last modification date: 2023-11-29)
Primary citation	Yang, X.,Hu, T.,Yang, X.,Xu, W.,Yang, H.,Guddat, L.W.,Zhang, B.,Rao, Z. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. J.Mol.Biol., 432:4426-4434, 2020 Cited by PubMed: 32512002 DOI: 10.1016/j.jmb.2020.05.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.82 Å)

Structure validation