7BMJ

Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 5-fluoropyridine-2,4-dicarboxylic acid, and factor X substrate peptide fragment (39mer-4Ser)

Summary for 7BMJ

Entry DOI	10.2210/pdb7bmj/pdb
Descriptor	Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	103481.15
Authors	Nakashima, Y.,Brewitz, L.,Schofield, C.J. (deposition date: 2021-01-20, release date: 2021-06-02, Last modification date: 2024-01-31)
Primary citation	Brewitz, L.,Nakashima, Y.,Tumber, A.,Salah, E.,Schofield, C.J. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases J Fluor Chem, 247:109804-, 2021 Cited by DOI: 10.1016/j.jfluchem.2021.109804 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation