7B4J
Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines
Summary for 7B4J
Entry DOI | 10.2210/pdb7b4j/pdb |
Descriptor | Aspartate aminotransferase family protein, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID, ... (4 entities in total) |
Functional Keywords | aminotransferase, transaminase, amines synthesis, enantioselective, thermostable, engineered, transferase |
Biological source | Pseudomonas sp. |
Total number of polymer chains | 2 |
Total formula weight | 101863.98 |
Authors | Capra, N.,Rozeboom, H.J.,Thunnissen, A.M.W.H.,Janssen, D.B. (deposition date: 2020-12-02, release date: 2021-09-01, Last modification date: 2021-09-22) |
Primary citation | Meng, Q.,Ramirez-Palacios, C.,Capra, N.,Hooghwinkel, M.E.,Thallmair, S.,Rozeboom, H.J.,Thunnissen, A.W.H.,Wijma, H.J.,Marrink, S.J.,Janssen, D.B. Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines. Acs Catalysis, 11:10733-10747, 2021 Cited by PubMed: 34504735DOI: 10.1021/acscatal.1c02053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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