7AKO

Crystal structure of CHK1 kinase domain in complex with a CLASPIN phosphopeptide

Summary for 7AKO

• Entry DOI: 10.2210/pdb7ako/pdb
• Descriptor: Serine/threonine-protein kinase Chk1, Claspin, STAUROSPORINE, ... (6 entities in total)
• Functional Keywords: cell cycle
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 73939.69

Authors

Day, M.,Oliver, A.W.,Pearl, L.H. (deposition date: 2020-10-01, release date: 2021-04-14, Last modification date: 2024-01-31)

• Primary citation: Day, M.,Parry-Morris, S.,Houghton-Gisby, J.,Oliver, A.W.,Pearl, L.H.; Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein.; Structure, 29:531-, 2021; PubMed: 33789090; DOI: 10.1016/j.str.2021.03.007

Experimental method

X-RAY DIFFRACTION (1.8 Å)