6XFM

Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of FUS

Summary for 6XFM

Entry DOI	10.2210/pdb6xfm/pdb
EMDB information	22169
Descriptor	RNA-binding protein FUS (1 entity in total)
Functional Keywords	low complexity domain, protein aggregation, amyloid fibril, rna binding protein, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	80198.27
Authors	Tycko, R.,Lee, M.,Ghosh, U.,Thurber, K.,Kato, M. (deposition date: 2020-06-15, release date: 2020-10-07, Last modification date: 2024-03-06)
Primary citation	Lee, M.,Ghosh, U.,Thurber, K.R.,Kato, M.,Tycko, R. Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS. Nat Commun, 11:5735-5735, 2020 Cited by PubMed: 33184287 DOI: 10.1038/s41467-020-19512-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.62 Å)

Structure validation