6X3K

Hsa Siglec and Unique domains in complex with 6S-sialy-Lewisx

Summary for 6X3K

• Entry DOI: 10.2210/pdb6x3k/pdb
• Descriptor: Streptococcal hemagglutinin, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, SODIUM ION, ... (5 entities in total)
• Functional Keywords: adhesin, serine rich repeat adhesin, bacterial adhesion, protein, cell adhesion
• Biological source: Streptococcus gordonii str. Challis
• Total number of polymer chains: 1
• Total formula weight: 26825.17

Authors

Stubbs, H.E.,Iverson, T.M. (deposition date: 2020-05-21, release date: 2021-05-26, Last modification date: 2023-10-18)

• Primary citation: Bensing, B.A.,Stubbs, H.E.,Agarwal, R.,Yamakawa, I.,Luong, K.,Solakyildirim, K.,Yu, H.,Hadadianpour, A.,Castro, M.A.,Fialkowski, K.P.,Morrison, K.M.,Wawrzak, Z.,Chen, X.,Lebrilla, C.B.,Baudry, J.,Smith, J.C.,Sullam, P.M.,Iverson, T.M.; Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation.; Nat Commun, 13:2753-2753, 2022; PubMed: 35585145; DOI: 10.1038/s41467-022-30509-y

Experimental method

X-RAY DIFFRACTION (2.5 Å)