6WRU
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
Summary for 6WRU
Entry DOI | 10.2210/pdb6wru/pdb |
Related | 6WQN 6WQQ 6WRS |
EMDB information | 21888 |
Descriptor | 50S ribosomal protein L19, 50S ribosomal protein L29, 50S ribosomal protein L3, ... (29 entities in total) |
Functional Keywords | antibiotic, tedizolid, oxazolidinone, ribosome |
Biological source | Staphylococcus aureus More |
Total number of polymer chains | 28 |
Total formula weight | 1315436.25 |
Authors | Belousoff, M.J. (deposition date: 2020-04-30, release date: 2020-06-03, Last modification date: 2020-12-16) |
Primary citation | Wright, A.,Deane-Alder, K.,Marschall, E.,Bamert, R.,Venugopal, H.,Lithgow, T.,Lupton, D.W.,Belousoff, M.J. Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM. Acs Pharmacol Transl Sci, 3:425-432, 2020 Cited by PubMed: 32566908DOI: 10.1021/acsptsci.0c00041 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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