6WQQ

Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid

Summary for 6WQQ

• Entry DOI: 10.2210/pdb6wqq/pdb
• Related: 6WQN
• EMDB information: 21873
• Descriptor: 50S ribosomal protein L19, 50S ribosomal protein L29, 50S ribosomal protein L3, ... (28 entities in total)
• Functional Keywords: antibiotic, radezolid, oxazolidinone, ribosome
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 27
• Total formula weight: 1295987.14

Authors

Belousoff, M.J. (deposition date: 2020-04-29, release date: 2020-06-03, Last modification date: 2020-12-16)

• Primary citation: Wright, A.,Deane-Alder, K.,Marschall, E.,Bamert, R.,Venugopal, H.,Lithgow, T.,Lupton, D.W.,Belousoff, M.J.; Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.; Acs Pharmacol Transl Sci, 3:425-432, 2020; PubMed: 32566908; DOI: 10.1021/acsptsci.0c00041

Experimental method

ELECTRON MICROSCOPY (3.1 Å)