6W6O

NaChBac-Nav1.7VSDII chimera and HWTX-IV complex

Summary for 6W6O

• Entry DOI: 10.2210/pdb6w6o/pdb
• EMDB information: 21560
• Descriptor: NaChBac-Nav1.7VSDII chimera, Huwentoxin-IV, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (3 entities in total)
• Functional Keywords: nachbac, channels, sodium ion-selective, transport protein-toxin complex, transport protein/toxin
• Biological source: Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125); More
• Total number of polymer chains: 8
• Total formula weight: 153211.15

Authors

Yan, N.,Gao, S. (deposition date: 2020-03-17, release date: 2020-06-24, Last modification date: 2021-01-13)

• Primary citation: Gao, S.,Valinsky, W.C.,On, N.C.,Houlihan, P.R.,Qu, Q.,Liu, L.,Pan, X.,Clapham, D.E.,Yan, N.; Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc.; Proc.Natl.Acad.Sci.USA, 117:14187-14193, 2020; PubMed: 32513729; DOI: 10.1073/pnas.1922903117

Experimental method

ELECTRON MICROSCOPY (3.2 Å)