6TQT

The crystal structure of the MSP domain of human MOSPD2.

Summary for 6TQT

Entry DOI	10.2210/pdb6tqt/pdb
Descriptor	Motile sperm domain-containing protein 2, 1,2-ETHANEDIOL, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	membrane contact sites, ffat motif, msp domain, endoplasmic reticulum, protein binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	24520.60
Authors	McEwen, A.G.,Poussin-Courmontagne, P.,Di Mattia, T.,Wendling, C.,Cavarelli, J.,Tomasetto, C.,Alpy, F. (deposition date: 2019-12-17, release date: 2020-11-18, Last modification date: 2024-01-24)
Primary citation	Di Mattia, T.,Martinet, A.,Ikhlef, S.,McEwen, A.G.,Nomine, Y.,Wendling, C.,Poussin-Courmontagne, P.,Voilquin, L.,Eberling, P.,Ruffenach, F.,Cavarelli, J.,Slee, J.,Levine, T.P.,Drin, G.,Tomasetto, C.,Alpy, F. FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts. Embo J., 39:e104369-e104369, 2020 Cited by PubMed: 33124732 DOI: 10.15252/embj.2019104369 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation