6SJC
Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine
Summary for 6SJC
Entry DOI | 10.2210/pdb6sjc/pdb |
Related | 6HDZ 6HE1 6HE3 6HHV 6HHW 6HHX 6HHY 6HHZ 6HI0 6RLT 6RLU 6RLV |
Descriptor | Aspartate--tRNA(Asp) ligase, 5'-O-(L-alpha-aspartylsulfamoyl)adenosine (3 entities in total) |
Functional Keywords | protein-inhibitor complex, trna aminoacylation, ligase |
Biological source | Thermus thermophilus |
Total number of polymer chains | 2 |
Total formula weight | 133286.47 |
Authors | De Graef, S.,Pang, L.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2019-08-13, release date: 2020-01-08, Last modification date: 2024-01-24) |
Primary citation | Pang, L.,Nautiyal, M.,De Graef, S.,Gadakh, B.,Zorzini, V.,Economou, A.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15:407-415, 2020 Cited by PubMed: 31869198DOI: 10.1021/acschembio.9b00887 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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