6RPU

Structure of the ternary complex of the IMPDH enzyme from Ashbya gossypii bound to the dinucleoside polyphosphate Ap5G and GDP

Summary for 6RPU

• Entry DOI: 10.2210/pdb6rpu/pdb
• Descriptor: Inosine-5'-monophosphate dehydrogenase, P1-(5'-ADENOSYL)-P5-(5'-GUANOSYL) PENTAPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: imp dehydrogenase, bateman domain, dinucleoside polyphosphate, oxidoreductase
• Biological source: Eremothecium gossypii ATCC 10895
• Total number of polymer chains: 1
• Total formula weight: 58138.18

Authors

Buey, R.M.,Fernandez-Justel, D.,Revuelta, J.L. (deposition date: 2019-05-14, release date: 2019-08-28, Last modification date: 2024-01-24)

• Primary citation: Fernandez-Justel, D.,Pelaez, R.,Revuelta, J.L.,Buey, R.M.; The Bateman domain of IMP dehydrogenase is a binding target for dinucleoside polyphosphates.; J.Biol.Chem., 294:14768-14775, 2019; PubMed: 31416831; DOI: 10.1074/jbc.AC119.010055

Experimental method

X-RAY DIFFRACTION (2.11 Å)