6QS4

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.

Summary for 6QS4

Entry DOI	10.2210/pdb6qs4/pdb
EMDB information	4621 4622 4623 4624 4625 4626 4627
Descriptor	Chaperone protein ClpB, casein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	disaggregase, proteostasis, aaa, chaperone
Biological source	Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W) More
Total number of polymer chains	7
Total formula weight	581536.31
Authors	Deville, C.,Saibil, H.R. (deposition date: 2019-02-20, release date: 2019-07-03, Last modification date: 2019-12-18)
Primary citation	Deville, C.,Franke, K.,Mogk, A.,Bukau, B.,Saibil, H.R. Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. Cell Rep, 27:3433-3446.e4, 2019 Cited by PubMed: 31216466 DOI: 10.1016/j.celrep.2019.05.075 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation