6PHC

Pfs25 in complex with the human transmission blocking antibody 2544

Summary for 6PHC

• Entry DOI: 10.2210/pdb6phc/pdb
• Related: 6PHB
• Descriptor: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, 2544 Antibody Fab, Light Chain, ... (4 entities in total)
• Functional Keywords: fab, complex, antigen, immunoglobulin, immune system
• Biological source: Plasmodium falciparum; More
• Total number of polymer chains: 6
• Total formula weight: 137424.51

Authors

McLeod, B.R.,Julien, J.P. (deposition date: 2019-06-25, release date: 2019-10-02, Last modification date: 2024-04-03)

• Primary citation: McLeod, B.,Miura, K.,Scally, S.W.,Bosch, A.,Nguyen, N.,Shin, H.,Kim, D.,Volkmuth, W.,Ramisch, S.,Chichester, J.A.,Streatfield, S.,Woods, C.,Schief, W.R.,Emerling, D.,King, C.R.,Julien, J.P.; Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.; Nat Commun, 10:4328-4328, 2019; PubMed: 31551421; DOI: 10.1038/s41467-019-11980-6

Experimental method

X-RAY DIFFRACTION (2.9 Å)