6PHB

Pfs25 in complex with the human transmission blocking antibody 2530

Summary for 6PHB

Entry DOI	10.2210/pdb6phb/pdb
Descriptor	25 kDa ookinete surface antigen, 2530 Antibody Fab, Light Chain, 2530 Antibody Fab, Heavy Chain, ... (5 entities in total)
Functional Keywords	fab, complex, antigen, immunoglobulin, immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	6
Total formula weight	135329.87
Authors	McLeod, B.R.,Julien, J.P. (deposition date: 2019-06-25, release date: 2019-10-02, Last modification date: 2023-10-11)
Primary citation	McLeod, B.,Miura, K.,Scally, S.W.,Bosch, A.,Nguyen, N.,Shin, H.,Kim, D.,Volkmuth, W.,Ramisch, S.,Chichester, J.A.,Streatfield, S.,Woods, C.,Schief, W.R.,Emerling, D.,King, C.R.,Julien, J.P. Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nat Commun, 10:4328-4328, 2019 Cited by PubMed: 31551421 DOI: 10.1038/s41467-019-11980-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation