6MEB

Crystal structure of Tylonycteris bat coronavirus HKU4 macrodomain in complex with nicotinamide adenine dinucleotide (NAD+)

Summary for 6MEB

Entry DOI	10.2210/pdb6meb/pdb
Related	6MEA 6MEN
Descriptor	Replicase polyprotein 1ab, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	coronavirus, macrodomain, adp-ribose, adp-ribosylhydrolase, hydrolase
Biological source	Bat coronavirus HKU4 (BtCoV)
Total number of polymer chains	2
Total formula weight	38517.11
Authors	Hammond, R.G.,Schormann, N.,McPherson, R.L.,Leung, A.K.L.,Deivanayagam, C.C.S.,Johnson, M.A. (deposition date: 2018-09-06, release date: 2019-09-11, Last modification date: 2023-10-11)
Primary citation	Hammond, R.G.,Schormann, N.,McPherson, R.L.,Leung, A.K.L.,Deivanayagam, C.,Johnson, M.A. ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4 Proc.Natl.Acad.Sci.USA, 2021 Cited by DOI: 10.1073/pnas.2004500118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation