6MEA
Crystal structure of a Tylonycteris bat coronavirus HKU4 macrodomain in complex with adenosine diphosphate ribose (ADP-ribose)
Summary for 6MEA
| Entry DOI | 10.2210/pdb6mea/pdb |
| Related | 6MEB 6MEN |
| Descriptor | Replicase polyprotein 1ab, ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total) |
| Functional Keywords | coronavirus, macrodomain, adp-ribose, adp-ribosylhydrolase, hydrolase |
| Biological source | Bat coronavirus HKU4 (BtCoV) |
| Total number of polymer chains | 2 |
| Total formula weight | 38308.89 |
| Authors | Hammond, R.G.,Schormann, N.,McPherson, R.L.,Leung, A.K.L.,Deivanayagam, C.C.S.,Johnson, M.A. (deposition date: 2018-09-06, release date: 2019-09-11, Last modification date: 2023-10-11) |
| Primary citation | Hammond, R.G.,Schormann, N.,McPherson, R.L.,Leung, A.K.L.,Deivanayagam, C.,Johnson, M.A. ADP-Ribose and Analogues bound to the DeMARylating Macrodomain from the Bat Coronavirus HKU4 Proc.Natl.Acad.Sci.USA, 2021 Cited by DOI: 10.1073/pnas.2004500118PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
Download full validation report
