6M84

Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2

Summary for 6M84

Entry DOI	10.2210/pdb6m84/pdb
Descriptor	ATP-sensitive inward rectifier potassium channel 12, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... (5 entities in total)
Functional Keywords	metal transport, kir 2.2 force open mutant, complex
Biological source	Gallus gallus (Chicken)
Total number of polymer chains	1
Total formula weight	40968.56
Authors	Lee, S.-J.,Ren, F.,Yuan, P.,Nichols, C.G. (deposition date: 2018-08-21, release date: 2019-09-04, Last modification date: 2023-10-11)
Primary citation	Zangerl-Plessl, E.M.,Lee, S.J.,Maksaev, G.,Bernsteiner, H.,Ren, F.,Yuan, P.,Stary-Weinzinger, A.,Nichols, C.G. Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152:-, 2020 Cited by PubMed: 31744859 DOI: 10.1085/jgp.201912422 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation