6M84
Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ATP-sensitive inward rectifier potassium channel 12 | polymer | 343 | 39476.8 | 1 | UniProt (F1NHE9) Pfam (PF01007) Pfam (PF17655) In PDB | Gallus gallus (Chicken) | Inward rectifier K(+) channel Kir2.2,Potassium channel,inwardly rectifying subfamily J member 12 |
| 2 | A | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 3 | A | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 1 | Chemie (PIO) | |||
| 4 | A | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 5 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 38 - 369 (UniProt: F1NHE9)
| PDB | External Database | Details |
|---|---|---|
| Met 36 | - | initiating methionine |
| Ala 37 | - | insertion |
| Trp 62 | Lys 62 | engineered mutation |
| Asp 178 | Gly 178 | engineered mutation |
| Ser 370 | - | cloning artifact |
| Asn 371 | - | cloning artifact |
| Ser 372 | - | cloning artifact |
| Leu 373 | - | cloning artifact |
| Glu 374 | - | cloning artifact |
| Val 375 | - | cloning artifact |
| Leu 376 | - | cloning artifact |
| Phe 377 | - | cloning artifact |
| Gln 378 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39476.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1491.8 | |
| All* | Total formula weight | 40968.6 |
