6J88

Crystal structure of HinD with benzo[b]thiophen analog

Summary for 6J88

• Entry DOI: 10.2210/pdb6j88/pdb
• Descriptor: Nocardicin N-oxygenase, PROTOPORPHYRIN IX CONTAINING FE, N-[(2S)-1-(1-benzothiophen-3-yl)-3-hydroxypropan-2-yl]-N~2~-methyl-L-valinamide, ... (4 entities in total)
• Functional Keywords: p450, indolactam, oxidation, oxidoreductase
• Biological source: Streptoalloteichus hindustanus
• Total number of polymer chains: 2
• Total formula weight: 97725.26

Authors

Fei, H.,Mori, T.,Abe, I. (deposition date: 2019-01-18, release date: 2019-08-07, Last modification date: 2023-11-22)

• Primary citation: He, F.,Mori, T.,Morita, I.,Nakamura, H.,Alblova, M.,Hoshino, S.,Awakawa, T.,Abe, I.; Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis.; Nat.Chem.Biol., 15:1206-1213, 2019; PubMed: 31636430; DOI: 10.1038/s41589-019-0380-9

Experimental method

X-RAY DIFFRACTION (2.35 Å)