6IEG
Crystal structure of human MTR4
Summary for 6IEG
Entry DOI | 10.2210/pdb6ieg/pdb |
Descriptor | Exosome RNA helicase MTR4, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION (3 entities in total) |
Functional Keywords | rna helicase, mtr4, rna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 229228.20 |
Authors | Chen, J.Y.,Yun, C.H. (deposition date: 2018-09-14, release date: 2019-04-03, Last modification date: 2023-11-22) |
Primary citation | Wang, J.,Chen, J.,Wu, G.,Zhang, H.,Du, X.,Chen, S.,Zhang, L.,Wang, K.,Fan, J.,Gao, S.,Wu, X.,Zhang, S.,Kuai, B.,Zhao, P.,Chi, B.,Wang, L.,Li, G.,Wong, C.C.L.,Zhou, Y.,Li, J.,Yun, C.,Cheng, H. NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. Genes Dev., 33:536-549, 2019 Cited by PubMed: 30842217DOI: 10.1101/gad.322602.118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.55 Å) |
Structure validation
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