6GFI
Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V
Summary for 6GFI
| Entry DOI | 10.2210/pdb6gfi/pdb |
| Descriptor | PRSS3 protein, Amyloid-beta A4 protein, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | protein protein interactions, serine proteases, amyloid protein precursor inhibitor, protein binding |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 66947.03 |
| Authors | Shahar, A.,Cohen, I.,Radisky, E.,Papo, N.,Naftaly, S. (deposition date: 2018-04-30, release date: 2018-09-12, Last modification date: 2024-01-17) |
| Primary citation | Naftaly, S.,Cohen, I.,Shahar, A.,Hockla, A.,Radisky, E.S.,Papo, N. Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries. Nat Commun, 9:3935-3935, 2018 Cited by PubMed: 30258049DOI: 10.1038/s41467-018-06403-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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