6FNW

Structure of a volume-regulated anion channel of the LRRC8 family

Summary for 6FNW

Entry DOI	10.2210/pdb6fnw/pdb
Descriptor	Volume-regulated anion channel subunit LRRC8A, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	ion channel, leucine-rich repeat domain, membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	48403.37
Authors	Deneka, D.,Sawicka, M.,Lam, A.K.M.,Paulino, C.,Dutzler, R. (deposition date: 2018-02-05, release date: 2018-05-16, Last modification date: 2024-05-08)
Primary citation	Deneka, D.,Sawicka, M.,Lam, A.K.M.,Paulino, C.,Dutzler, R. Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558:254-259, 2018 Cited by PubMed: 29769723 DOI: 10.1038/s41586-018-0134-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation