6DMM

Crystal structure of the G23A mutant of human alpha defensin HNP4.

Summary for 6DMM

Entry DOI	10.2210/pdb6dmm/pdb
Descriptor	Neutrophil defensin 4, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	human alpha-defensin, antimicrobial peptide, antimicrobial protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	12
Total formula weight	47163.88
Authors	Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2018-06-05, release date: 2019-01-30, Last modification date: 2023-10-11)
Primary citation	Hu, H.,Di, B.,Tolbert, W.D.,Gohain, N.,Yuan, W.,Gao, P.,Ma, B.,He, Q.,Pazgier, M.,Zhao, L.,Lu, W. Systematic mutational analysis of human neutrophil alpha-defensin HNP4. Biochim Biophys Acta Biomembr, 1861:835-844, 2019 Cited by PubMed: 30658057 DOI: 10.1016/j.bbamem.2019.01.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation