6DMM

Crystal structure of the G23A mutant of human alpha defensin HNP4.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Neutrophil defensin 4	polymer	33	3734.5	12	UniProt (P12838) Pfam (PF00323) In PDB	Homo sapiens	Defensin,alpha 4,HNP-4,HP-4
2	J, K, L, A, B...	SULFATE ION	non-polymer		96.1	22	Chemie (SO4)
3	J, B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
4		water	water		18.0	284	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 33 (UniProt: P12838)

PDB	External Database	Details
Ala 23	Gly 86	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	44814.1
Non-Polymers*	Number of molecules	24
	Total formula weight	2349.7
All*	Total formula weight	47163.9

*Water molecules are not included.