5WGG

Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides

Summary for 5WGG

• Entry DOI: 10.2210/pdb5wgg/pdb
• Related: 5WHY
• Descriptor: Radical SAM domain protein, CteA, IRON/SULFUR CLUSTER, ... (6 entities in total)
• Functional Keywords: radical sam binding, metalloprotein, sciff maturase, spasm domain-containing, peptide binding protein
• Biological source: Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372); More
• Total number of polymer chains: 2
• Total formula weight: 56096.39

Authors

Grove, T.L.,Himes, P.,Bowers, A.,Bonanno, J.B.,Almo, S.C. (deposition date: 2017-07-14, release date: 2017-07-26, Last modification date: 2024-03-13)

• Primary citation: Grove, T.L.,Himes, P.M.,Hwang, S.,Yumerefendi, H.,Bonanno, J.B.,Kuhlman, B.,Almo, S.C.,Bowers, A.A.; Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.; J. Am. Chem. Soc., 139:11734-11744, 2017; PubMed: 28704043; DOI: 10.1021/jacs.7b01283

Experimental method

X-RAY DIFFRACTION (2.036 Å)