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5OX1

Glycogen Phosphorylase in complex with JLH270

Summary for 5OX1
Entry DOI10.2210/pdb5ox1/pdb
Related5OWY 5OWZ 5OX0
DescriptorGlycogen phosphorylase, muscle form, (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methoxyphenyl)-1~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywordstransferase
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains1
Total formula weight98085.00
Authors
Kyriakis, E.,Stravodimos, G.A.,Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Leonidas, D.D. (deposition date: 2017-09-05, release date: 2018-02-28)
Primary citationKyriakis, E.,Solovou, T.G.A.,Kun, S.,Czifrak, K.,Szocs, B.,Juhasz, L.,Bokor, E.,Stravodimos, G.A.,Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Skamnaki, V.T.,Somsak, L.,Leonidas, D.D.
Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg. Chem., 77:485-493, 2018
Cited by
PubMed: 29454281
DOI: 10.1016/j.bioorg.2018.02.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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