5OWY

Glycogen Phosphorylase in complex with KS252

Summary for 5OWY

Entry DOI	10.2210/pdb5owy/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid, ... (5 entities in total)
Functional Keywords	transferase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	98369.06
Authors	Kyriakis, E.,Stravodimos, G.,Kantsadi, A.,Chatzileontiadou, D.,Leonidas, D. (deposition date: 2017-09-05, release date: 2018-02-28)
Primary citation	Kyriakis, E.,Solovou, T.G.A.,Kun, S.,Czifrak, K.,Szocs, B.,Juhasz, L.,Bokor, E.,Stravodimos, G.A.,Kantsadi, A.L.,Chatzileontiadou, D.S.M.,Skamnaki, V.T.,Somsak, L.,Leonidas, D.D. Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77:485-493, 2018 Cited by PubMed: 29454281 DOI: 10.1016/j.bioorg.2018.02.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation