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5NUI

Crystal structure of SIVmac239 Nef in an ExxxLM endocytic sorting motif bound state

Summary for 5NUI
Entry DOI10.2210/pdb5nui/pdb
Related5NUH
DescriptorProtein Nef, SER-GLN-ILE-LYS-ARG-LEU-LEU-SER (3 entities in total)
Functional Keywordssiv, nef, endocytic sorting motif, exxxll, viral protein
Biological sourceSimian immunodeficiency virus (SIV)
More
Total number of polymer chains3
Total formula weight36670.91
Authors
Manrique, S.,Horenkamp, F.A.,Anand, K.,Geyer, M. (deposition date: 2017-04-30, release date: 2017-08-16, Last modification date: 2024-01-17)
Primary citationManrique, S.,Sauter, D.,Horenkamp, F.A.,Lulf, S.,Yu, H.,Hotter, D.,Anand, K.,Kirchhoff, F.,Geyer, M.
Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3.
Nat Commun, 8:442-442, 2017
Cited by
PubMed: 28874665
DOI: 10.1038/s41467-017-00481-z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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