5NM9
Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site.
Summary for 5NM9
| Entry DOI | 10.2210/pdb5nm9/pdb |
| Related | 5MEY 5MEZ 5MF0 |
| Descriptor | Mothers against decapentaplegic homolog, DNA (5'-D(P*AP*TP*GP*CP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*GP*CP*AP*T)-3'), ZINC ION, ... (4 entities in total) |
| Functional Keywords | smads, transcription factor, dna complex, transcription |
| Biological source | Trichoplax adhaerens More |
| Cellular location | Cytoplasm . Nucleus : B3S7S5 |
| Total number of polymer chains | 4 |
| Total formula weight | 43138.81 |
| Authors | Kaczmarska, Z.,Freier, R.,Marquez, J.A.,Macias, M.J. (deposition date: 2017-04-05, release date: 2017-11-15, Last modification date: 2024-01-17) |
| Primary citation | Martin-Malpartida, P.,Batet, M.,Kaczmarska, Z.,Freier, R.,Gomes, T.,Aragon, E.,Zou, Y.,Wang, Q.,Xi, Q.,Ruiz, L.,Vea, A.,Marquez, J.A.,Massague, J.,Macias, M.J. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8:2070-2070, 2017 Cited by PubMed: 29234012DOI: 10.1038/s41467-017-02054-6 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.43 Å) |
Structure validation
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