5LKT

Crystal structure of the p300 acetyltransferase catalytic core with butyryl-coenzyme A.

Summary for 5LKT

• Entry DOI: 10.2210/pdb5lkt/pdb
• Related: 4BHW
• Descriptor: Histone acetyltransferase p300,Histone acetyltransferase p300, ZINC ION, Butyryl Coenzyme A, ... (7 entities in total)
• Functional Keywords: p300 acetyltransferase, butyryl-coa, chromatin modification, acylation, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: Q09472
• Total number of polymer chains: 1
• Total formula weight: 68591.82

Authors

Kaczmarska, Z.,Ortega, E.,Marquez, J.A.,Panne, D. (deposition date: 2016-07-24, release date: 2016-11-02, Last modification date: 2024-01-10)

• Primary citation: Kaczmarska, Z.,Ortega, E.,Goudarzi, A.,Huang, H.,Kim, S.,Marquez, J.A.,Zhao, Y.,Khochbin, S.,Panne, D.; Structure of p300 in complex with acyl-CoA variants.; Nat. Chem. Biol., 13:21-29, 2017; PubMed: 27820805; DOI: 10.1038/nchembio.2217

Experimental method

X-RAY DIFFRACTION (2.04 Å)