5KZ5

Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery: the Complex Formed by the Iron Donor, the Sulfur Donor, and the Scaffold

Summary for 5KZ5

Entry DOI	10.2210/pdb5kz5/pdb
EMDB information	8293 8301
Descriptor	Cysteine desulfurase, mitochondrial, Frataxin, mitochondrial, Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (3 entities in total)
Functional Keywords	frataxin, iron-sulfur protein, mitochondria, protein complex, transferase-oxidoreductase complex, transferase/oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	36
Total formula weight	897651.04
Authors	Gakh, O.,Ranatunga, W.,Smith, D.Y.,Ahlgren, E.C.,Al-Karadaghi, S.,Thompson, J.R.,Isaya, G. (deposition date: 2016-07-22, release date: 2016-08-31, Last modification date: 2019-12-18)
Primary citation	Gakh, O.,Ranatunga, W.,Smith, D.Y.,Ahlgren, E.C.,Al-Karadaghi, S.,Thompson, J.R.,Isaya, G. Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. J.Biol.Chem., 291:21296-21321, 2016 Cited by PubMed: 27519411 DOI: 10.1074/jbc.M116.738542 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (14.3 Å)

Structure validation