5K8B

X-ray structure of KdnA, 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase, from Shewanella oneidensis in the presence of the external aldimine with PLP and glutamate

Summary for 5K8B

• Entry DOI: 10.2210/pdb5k8b/pdb
• Related: 5K8C
• Descriptor: 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: transaminase, 8-amino-3, 8-dideoxy-d-manno-octulosonic acid, deoxy sugar, transferase
• Biological source: Shewanella oneidensis (strain MR-1)
• Total number of polymer chains: 4
• Total formula weight: 180786.43

Authors

Holden, H.M.,Thoden, J.B.,Zachman-Brockmeyer, T.R. (deposition date: 2016-05-28, release date: 2016-06-15, Last modification date: 2023-09-27)

• Primary citation: Zachman-Brockmeyer, T.R.,Thoden, J.B.,Holden, H.M.; Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid.; Biochemistry, 55:4485-4494, 2016; PubMed: 27275764; DOI: 10.1021/acs.biochem.6b00439

Experimental method

X-RAY DIFFRACTION (2.15 Å)