5JXQ

TRNA-GUANINE TRANSGLYCOSYLASE (TGT) IN COMPLEX WITH 6-AMINO-2-{[4-(2-HYDROXYETHYL)PHENETHYL]AMINO}-1,7-DIHYDRO-8H-IMIDAZO[4,5-g]QUINAZOLIN-8-ONE

Summary for 5JXQ

• Entry DOI: 10.2210/pdb5jxq/pdb
• Related: 4Q8T 4Q8U 4Q8V 4Q8W
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: guanine exchange enzyme, preq1, trna, transferase-transferase, inhibitor complex, transferase
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43667.25

Authors

Neeb, M.,Heine, A.,Klebe, G. (deposition date: 2016-05-13, release date: 2016-08-10, Last modification date: 2024-01-10)

• Primary citation: Neeb, M.,Hohn, C.,Ehrmann, F.R.,Hartsch, A.,Heine, A.,Diederich, F.,Klebe, G.; Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding?; Bioorg.Med.Chem., 24:4900-4910, 2016; PubMed: 27501913; DOI: 10.1016/j.bmc.2016.07.053

Experimental method

X-RAY DIFFRACTION (1.2 Å)