4Q8W

tRNA-Guanine Transglycosylase (TGT) in Complex with 4-[2-({6-Amino-8-oxo-1H,7H,8H-imidazo[4,5-g]quinazolin-2-yl}amino)ethyl]benzoic acid

Summary for 4Q8W

• Entry DOI: 10.2210/pdb4q8w/pdb
• Related: 1P0D 4Q8T 4Q8U 4Q8V
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 4-{2-[(6-amino-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-2-yl)amino]ethyl}benzoic acid, ... (5 entities in total)
• Functional Keywords: guanine exchange enzyme, preq1, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43867.97

Authors

Neeb, M.,Heine, A.,Klebe, G. (deposition date: 2014-04-28, release date: 2015-05-20, Last modification date: 2023-09-20)

• Primary citation: Neeb, M.,Hohn, C.,Heine, A.,Diederich, F.,Klebe, G.; Addressing a New Subpocket of TGT by Elongated 2-Amino-lin-benzoguanines; To be Published,

Experimental method

X-RAY DIFFRACTION (1.14 Å)