5H2R

Crystal structure of T brucei phosphodiesterase B2 bound to compound 15b

Summary for 5H2R

• Entry DOI: 10.2210/pdb5h2r/pdb
• Related: 5H2Q
• Descriptor: Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: phosphodiesterase inhibitor trypanosoma brucei, hydrolase
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 2
• Total formula weight: 78210.50

Authors

Noble, C.G. (deposition date: 2016-10-17, release date: 2017-11-01, Last modification date: 2023-11-08)

• Primary citation: Ng, P.S.,Noble, C.G.,Ng, F.S.B.,Chew, S.H.,Lim, C.C.,Manoharan, V.,Wan, K.F.,Vachaspati, P.,Kaiser, M.,Ma, N.L.,Gedeck, P.,Kounde, C.,Rao, S.P.S.; Trypanosomal Phosphodiesterase B1 and B2 as a Potential Therapy for Human African Trypanosomiasis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)