5F41

DENGUE SEROTYPE 3 RNA-DEPENDENT RNA POLYMERASE BOUND TO FD-83-KI26

Summary for 5F41

Entry DOI	10.2210/pdb5f41/pdb
Related	5F3Z 5FST
Descriptor	Genome polyprotein, ZINC ION, 2-(4-methoxy-3-thiophen-3-yl-phenyl)ethanoic acid, ... (4 entities in total)
Functional Keywords	inhibitor rdrp, dengue virus, transferase
Biological source	Dengue virus 3
Cellular location	Virion membrane ; Multi-pass membrane protein : Q6DLV0
Total number of polymer chains	1
Total formula weight	74003.98
Authors	Noble, C.G. (deposition date: 2015-12-03, release date: 2016-02-24, Last modification date: 2023-11-08)
Primary citation	Noble, C.G.,Lim, S.P.,Arora, R.,Yokokawa, F.,Nilar, S.,Seh, C.C.,Wright, S.K.,Benson, T.E.,Smith, P.W.,Shi, P.Y. A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening J.Biol.Chem., 291:8541-8548, 2016 Cited by PubMed: 26872970 DOI: 10.1074/jbc.M115.710731 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation