5F3Z

Dengue serotype 3 RNA-dependent RNA polymerase bound to PC-79-SH52

Summary for 5F3Z

• Entry DOI: 10.2210/pdb5f3z/pdb
• Related: 5F3T 5F41
• Descriptor: Genome polyprotein, ZINC ION, 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, ... (4 entities in total)
• Functional Keywords: rdrp inhibitor, dengue, transferase
• Biological source: Dengue virus 3
• Cellular location: Virion membrane ; Multi-pass membrane protein : Q6DLV0
• Total number of polymer chains: 1
• Total formula weight: 74003.98

Authors

Noble, C.G. (deposition date: 2015-12-03, release date: 2016-02-24, Last modification date: 2023-11-08)

• Primary citation: Noble, C.G.,Lim, S.P.,Arora, R.,Yokokawa, F.,Nilar, S.,Seh, C.C.,Wright, S.K.,Benson, T.E.,Smith, P.W.,Shi, P.Y.; A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening; J.Biol.Chem., 291:8541-8548, 2016; PubMed: 26872970; DOI: 10.1074/jbc.M115.710731

Experimental method

X-RAY DIFFRACTION (2 Å)