5EST

Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate

5EST の概要

• エントリーDOI: 10.2210/pdb5est/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000329
• 分子名称: ELASTASE, N~2~-[(benzyloxy)carbonyl]-N-[(1R,2S)-1-(dihydroxyboranyl)-2-methylbutyl]-L-alaninamide, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pig)
• 細胞内の位置: Secreted: P00772
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26400.36

構造登録者

Takahashi, L.H.,Radhakrishnan, R.,Rosenfieldjunior, R.E.,Meyerjunior, E.F. (登録日: 1989-05-15, 公開日: 1992-04-15, 最終更新日: 2012-12-12)

• 主引用文献: Takahashi, L.H.,Radhakrishnan, R.,Rosenfield Jr., R.E.,Meyer Jr., E.F.; Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate.; Biochemistry, 28:7610-7617, 1989; PubMed: 2611205; DOI: 10.1021/bi00445a016

実験手法

X-RAY DIFFRACTION (2.09 Å)