5EA8
Crystal Structure of Prefusion RSV F Glycoprotein Fusion Inhibitor Resistance Mutant D489Y
Summary for 5EA8
Entry DOI | 10.2210/pdb5ea8/pdb |
Related | 4MMU 5EA3 5EA4 5EA5 5EA6 5EA7 |
Descriptor | Fusion glycoprotein F0, SULFATE ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total) |
Functional Keywords | class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein, fusion inhibitor |
Biological source | Human respiratory syncytial virus A (strain A2) |
Total number of polymer chains | 1 |
Total formula weight | 64104.12 |
Authors | Battles, M.B.,McLellan, J.S.,Arnoult, E.,Roymans, D.,Langedijk, J.P. (deposition date: 2015-10-15, release date: 2015-12-09, Last modification date: 2023-09-27) |
Primary citation | Battles, M.B.,Langedijk, J.P.,Furmanova-Hollenstein, P.,Chaiwatpongsakorn, S.,Costello, H.M.,Kwanten, L.,Vranckx, L.,Vink, P.,Jaensch, S.,Jonckers, T.H.,Koul, A.,Arnoult, E.,Peeples, M.E.,Roymans, D.,McLellan, J.S. Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12:87-93, 2016 Cited by PubMed: 26641933DOI: 10.1038/nchembio.1982 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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