5DPT

Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117

Summary for 5DPT

Entry DOI	10.2210/pdb5dpt/pdb
Related	3X0W 5DPR 5DPS 5DPW
Descriptor	Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1, (4S)-2-METHYL-2,4-PENTANEDIOL (2 entities in total)
Functional Keywords	autophagy, chimeric protein, protein binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	31649.80
Authors	Ravichandran, A.C.,Suzuki, H.,Dobson, R.C.J. (deposition date: 2015-09-14, release date: 2016-09-28, Last modification date: 2024-03-06)
Primary citation	Rogov, V.V.,Stolz, A.,Ravichandran, A.C.,Rios-Szwed, D.O.,Suzuki, H.,Kniss, A.,Lohr, F.,Wakatsuki, S.,Dotsch, V.,Dikic, I.,Dobson, R.C.,McEwan, D.G. Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep., 18:1382-1396, 2017 Cited by PubMed: 28655748 DOI: 10.15252/embr.201643587 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation