3X0W
Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119
Summary for 3X0W
Entry DOI | 10.2210/pdb3x0w/pdb |
Descriptor | Microtubule-associated proteins 1A/1B light chain 3B (2 entities in total) |
Functional Keywords | ubiquitin-like fold, autophagy, plekhm1, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton: Q9GZQ8 |
Total number of polymer chains | 2 |
Total formula weight | 31463.77 |
Authors | Suzuki, H.,McEwan, D.G.,Popovic, D.,Gubas, A.,Terawaki, S.,Stadel, D.,Coxon, F.,Stegmann, D.M.,Bhogaraju, S.,Maddi, K.,Kirchhoff, A.,Gatti, E.,Helfrich, M.H.,Behrends, C.,Pierre, P.,Dikic, I.,Wakatsuki, S. (deposition date: 2014-10-22, release date: 2015-01-14, Last modification date: 2023-11-08) |
Primary citation | McEwan, D.G.,Popovic, D.,Gubas, A.,Terawaki, S.,Suzuki, H.,Stadel, D.,Coxon, F.P.,Miranda de Stegmann, D.,Bhogaraju, S.,Maddi, K.,Kirchof, A.,Gatti, E.,Helfrich, M.H.,Wakatsuki, S.,Behrends, C.,Pierre, P.,Dikic, I. PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol.Cell, 57:39-54, 2015 Cited by PubMed: 25498145DOI: 10.1016/j.molcel.2014.11.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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