5DLY

Crystal structure of the plantazolicin methyltransferase BamL in complex with monoazolic desmethylPZN analog and SAH

5DLY の概要

• エントリーDOI: 10.2210/pdb5dly/pdb
• 関連するPDBエントリー: 5DLY 5DM1 5DM2 5DM4
• 分子名称: plantazolicin methyltransferase BamL, prop-2-en-1-yl 2-[(1S)-1-amino-4-carbamimidamidobutyl]-1,3-thiazole-4-carboxylate, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• 機能のキーワード: plantazolicin, n-methyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Bacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31014.04

構造登録者

Hao, Y.,Nair, S.K. (登録日: 2015-09-07, 公開日: 2015-09-30, 最終更新日: 2024-03-06)

• 主引用文献: Hao, Y.,Blair, P.M.,Sharma, A.,Mitchell, D.A.,Nair, S.K.; Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin.; ACS Chem. Biol., 10:1209-1216, 2015; PubMed: 25635336; DOI: 10.1021/cb501042a

実験手法

X-RAY DIFFRACTION (1.5 Å)