5C69
Crystal Structure of Prefusion-stabilized RSV F variant PR-DM
Summary for 5C69
Entry DOI | 10.2210/pdb5c69/pdb |
Related | 4ZYP 5C6B |
Descriptor | Fusion glycoprotein F0,Fibritin, SULFATE ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total) |
Functional Keywords | class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein |
Biological source | Human respiratory syncytial virus A More |
Total number of polymer chains | 1 |
Total formula weight | 55707.31 |
Authors | McLellan, J.S.,Langedijk, J.P.M. (deposition date: 2015-06-22, release date: 2015-09-23, Last modification date: 2023-09-27) |
Primary citation | Krarup, A.,Truan, D.,Furmanova-Hollenstein, P.,Bogaert, L.,Bouchier, P.,Bisschop, I.J.,Widjojoatmodjo, M.N.,Zahn, R.,Schuitemaker, H.,McLellan, J.S.,Langedijk, J.P. A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nat Commun, 6:8143-8143, 2015 Cited by PubMed: 26333350DOI: 10.1038/ncomms9143 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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