5C6B

Crystal Structure of Prefusion-stabilized RSV F variant SC-TM

Summary for 5C6B

Entry DOI	10.2210/pdb5c6b/pdb
Related	4ZYP 5C69
Descriptor	Fusion glycoprotein F0,Fibritin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ... (5 entities in total)
Functional Keywords	class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein
Biological source	Human respiratory syncytial virus A More
Total number of polymer chains	1
Total formula weight	55374.73
Authors	McLellan, J.S.,Langedijk, J.P.M. (deposition date: 2015-06-22, release date: 2015-09-23, Last modification date: 2023-09-27)
Primary citation	Krarup, A.,Truan, D.,Furmanova-Hollenstein, P.,Bogaert, L.,Bouchier, P.,Bisschop, I.J.,Widjojoatmodjo, M.N.,Zahn, R.,Schuitemaker, H.,McLellan, J.S.,Langedijk, J.P. A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nat Commun, 6:8143-8143, 2015 Cited by PubMed: 26333350 DOI: 10.1038/ncomms9143 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation