5BTV

Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS324

Summary for 5BTV

• Entry DOI: 10.2210/pdb5btv/pdb
• Related: 4FL5
• Descriptor: 14-3-3 protein sigma, Microtubule-associated protein tau - peptide pS324, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: peptide binding protein, 14-3-3, tau-protein, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27012.30

Authors

Ottmann, C.,Schumacher, B.,Bartel, M. (deposition date: 2015-06-03, release date: 2016-07-20, Last modification date: 2019-03-13)

• Primary citation: Joo, Y.,Schumacher, B.,Landrieu, I.,Bartel, M.,Smet-Nocca, C.,Jang, A.,Choi, H.S.,Jeon, N.L.,Chang, K.A.,Kim, H.S.,Ottmann, C.,Suh, Y.H.; Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau.; Faseb J., 29:4133-4144, 2015; PubMed: 26103986; DOI: 10.1096/fj.14-265009

Experimental method

X-RAY DIFFRACTION (1.7 Å)