5B2K
A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
Summary for 5B2K
| Entry DOI | 10.2210/pdb5b2k/pdb |
| Related | 5B2L 5B2M |
| Descriptor | Dual specificity mitogen-activated protein kinase kinase 7 (2 entities in total) |
| Functional Keywords | protein kinase, apo structure, auto-inhibition form, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 36998.90 |
| Authors | Sogabe, Y.,Hashimoto, T.,Matsumoto, T.,Kirii, Y.,Sawa, M.,Kinoshita, T. (deposition date: 2016-01-19, release date: 2016-04-06, Last modification date: 2023-11-08) |
| Primary citation | Sogabe, Y.,Hashimoto, T.,Matsumoto, T.,Kirii, Y.,Sawa, M.,Kinoshita, T. A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7 Biochem.Biophys.Res.Commun., 473:476-481, 2016 Cited by PubMed: 26987717DOI: 10.1016/j.bbrc.2016.03.036 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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